What are we trying to learn?
We publish the questions before we publish the answers. Every R3TA report maps back to one of the questions below, so readers can see what we set out to observe — and what we did not.
How does self-reported weight change over 4, 12, 24 and 26 weeks?
When do participants first report meaningful changes in hunger, satiety and food noise?
Which side effects are most commonly reported, when do they emerge, and how long do they persist?
Where available, how do fat mass and lean mass change over time?
How do participants report changes in energy, exercise, sleep and everyday activity?
Do people reporting previous semaglutide or tirzepatide use describe different experiences?
Why do participants report stopping?
Why do some people report dramatically different experiences from others?