RETA 10 mg/mL

The goal is safe, steady weight loss. Increasing the dose slowly reduces side effects, protects muscle mass, and prevents the kind of rapid weight loss that leads to fatigue, weakness, and nutritional deficits.

Inject once every 5 days and keep the spacing consistent.

Injecting every 5 days instead of once a week keeps the medication steadier in your system. This means more consistent appetite control, fewer side effects, and less of that "wearing off" feeling before your next shot.

Begin at 10 units (1 mg) for your first two injections.

After the first 10 days, increase the dose every third injection (every 15 days). Each increase adds 10 units (1 mg).

Continue this pattern until you reach the dose that delivers steady results.

If you are currently on tirzepatide, multiply your current weekly dose by 0.6 to find your retatrutide dose every 5 days.

Start at your equivalent dose from day one. No titration needed. Your body has already adjusted to this type of medication.

Weigh yourself every 7 days and use this to guide dose changes. In the first two weeks, weight loss of 3 to 5 lbs is common due to water and glycogen changes — this is not a reason to delay your first escalation.

Weight loss medications reduce appetite, which can lead to inadequate protein intake and muscle loss. Two things protect against this:

1. Protein — At least 1 gram per pound of your target body weight, every day. Prioritize protein at every meal.
2. Resistance Training — Lift weights or do bodyweight resistance exercises at least 2 to 3 times per week.

• You reach your target weight
• Weekly loss is consistently 2 lbs or more
• Persistent nausea or stomach discomfort
• Fatigue, weakness, dizziness, or dehydration
• Difficulty eating normal meals
• You reach the maximum dose (90 units / 9.0 mg)

Stay at the dose that controls hunger, holds weight loss at 1 to 2 lbs per week, and avoids side effects. If weight loss becomes too fast or symptoms develop, reduce by 10 units and reassess after 15 days.

If you miss a dose, take it as soon as possible and resume the 5-day spacing from that point. Do not double a dose.

• Inject every 5 days, same time of day
• Start at 10 units (1 mg) for your first two injections
• Increase by 10 units every third injection (every 15 days)
• Target 1 to 2 lbs of weight loss per week
• Eat at least 1 g protein per pound of target body weight daily
• Lift weights 2 to 3 times per week
• If switching from tirzepatide, multiply your weekly dose by 0.6 and inject every 5 days
• Stop escalation once target weight or safety limits are reached